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IL21R Polyclonal Antibody

CAT: 0866-RD84515A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD84515A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21) . It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
Description
This is a IL21R Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
IL21R, CD360, NILR
Gene ID
50615
Swiss Prot
Q9HBE5
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human IL21R (NP_851565.4) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
59 kDa
Observed Molecular Weight
70 kDa
Host or Source
Rabbit
Isotype
IgG

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