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ANAPC5 Polyclonal Antibody

CAT: 0866-RD84295A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD84295A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
Description
This is a ANAPC5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ANAPC5, APC5
Gene ID
51433
Swiss Prot
Q9UJX4
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ANAPC5 (NP_057321.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
25 kDa/72 kDa/85 kDa
Observed Molecular Weight
85 kDa
Host or Source
Rabbit
Isotype
IgG

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