MLPH Polyclonal Antibody

• Background:

  This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a MLPH Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MLPH, SLAC2-A

• Gene ID:

  79083

• Swiss Prot:

  Q9BV36

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human MLPH (NP_077006.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  50 kDa/52 kDa/60 kDa/62 kDa/65 kDa

• Observed Molecular Weight:

  75 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG