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CCM2 Polyclonal Antibody

CAT: 0866-RD83887A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83887A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
Description
This is a CCM2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CCM2, C7orf22, OSM, PP10187
Gene ID
83605
Swiss Prot
Q9BSQ5
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CCM2 (NP_113631.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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