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PHF21A Polyclonal Antibody

CAT: 0866-RD83743A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83743A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.
Description
This is a PHF21A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PHF21A, BHC80, BM-006
Gene ID
51317
Swiss Prot
Q96BD5
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PHF21A (NP_001095272.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
70 kDa/74 kDa
Observed Molecular Weight
70-80 kDa
Host or Source
Rabbit
Isotype
IgG

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