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FMR1 Polyclonal Antibody

CAT: 0866-RD83628A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83628A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1) . Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Description
This is a FMR1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
FMRP, FRAXA, POF, POF1, FMR1, POFX
Gene ID
2332
Swiss Prot
Q06787
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human FMR1 (NP_002015.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58 kDa/61 kDa/66 kDa/68 kDa/69 kDa/70 kDa/71 kDa
Observed Molecular Weight
71 kDa
Host or Source
Rabbit
Isotype
IgG

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