(KO Validated) HuR / ELAVL1 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.

• Description:

  This is a (KO Validated) HuR / ELAVL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ELAV1, HUR, Hua, MelG, HuR / ELAVL1, ELAVL1

• Gene ID:

  1994

• Swiss Prot:

  Q15717

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide of human HuR / ELAVL1 (NP_001410.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  36 kDa/38 kDa

• Observed Molecular Weight:

  36 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG