Norgestimate

• Description :

  Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive[1][2]. Norgestimate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H361

• Target :

  Progesterone Receptor

• Type :

  Reference compound

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/norgestimate.html

• Concentration :

  10mM

• Purity :

  99.57

• Solubility :

  DMSO : 87.5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  C#C[C@@]1(OC(C)=O)CC[C@@]2([H])[C@]3([H])CCC4=C/C(CC[C@]4([H])[C@@]3([H])CC[C@]12CC)=N/O

• Molecular Formula :

  C23H31NO3

• Molecular Weight :

  369.50

• Precautions :

  H302, H315, H319, H361

• References & Citations :

  [1]Stanczyk FZ, et al. All progestins are not created equal. Steroids. 2003 Nov;68 (10-13) :879-90.|[2]Phillips A, et al. Preclinical evaluation of norgestimate, a progestin with minimal androgenic activity. Am J Obstet Gynecol. 1992 Oct;167 (4 Pt 2) :1191-6.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [35189-28-7]