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Norgestimate

CAT: 0804-HY-W013172-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W013172-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive[1][2]. Norgestimate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
35189-28-7
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H361
Target
Progesterone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/norgestimate.html
Concentration
10mM
Purity
99.57
Solubility
DMSO : 87.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C#C[C@@]1(OC(C)=O)CC[C@@]2([H])[C@]3([H])CCC4=C/C(CC[C@]4([H])[C@@]3([H])CC[C@]12CC)=N/O
Molecular Formula
C23H31NO3
Molecular Weight
369.50
Precautions
H302, H315, H319, H361
References & Citations
[1]Stanczyk FZ, et al. All progestins are not created equal. Steroids. 2003 Nov;68 (10-13) :879-90.|[2]Phillips A, et al. Preclinical evaluation of norgestimate, a progestin with minimal androgenic activity. Am J Obstet Gynecol. 1992 Oct;167 (4 Pt 2) :1191-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched