METAP2 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a METAP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  METAP2, MAP2, MNPEP, p67eIF2

• Gene ID:

  10988

• Swiss Prot:

  P50579

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human METAP2 (NP_006829.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:200-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  50 kDa/52 kDa

• Observed Molecular Weight:

  60 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG