METAP2 Polyclonal Antibody

CAT: 0866-RD83596A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD83596A-01Size:60 μL
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Background
The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.
Description
This is a METAP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
METAP2, MAP2, MNPEP, p67eIF2
Gene ID
10988
Swiss Prot
P50579
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human METAP2 (NP_006829.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:200-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
50 kDa/52 kDa
Observed Molecular Weight
60 kDa
Host or Source
Rabbit
Isotype
IgG

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