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ATM Polyclonal Antibody

CAT: 0866-RD83576A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83576A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
Description
This is a ATM Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1, ATM
Gene ID
472
Swiss Prot
Q13315
Reactivity
Human
Immunogen
A synthetic peptide of human ATM (NP_000042.3) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
350 kDa
Observed Molecular Weight
310 kDa
Host or Source
Rabbit
Isotype
IgG

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