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NPRL2 Polyclonal Antibody

CAT: 0866-RD83548A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83548A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NPRL2, also known as TUSC4 (tumor suppressor candidate 4), is a 380 amino acid protein that contains a bipartite nuclear localization signal and a granulin protein-binding domain. It is highly expressed in skeletal muscle, followed by brain, liver and pancreas, with lower expression in lung, kidney, placenta and heart. NPRL2 is also expressed in most lung cancer cell lines and may be involved in tumor suppression. NPRL2 may play a role in mismatch repair, cell cycle checkpoint signaling and activation of apoptotic pathways. It may also enhance the therapeutic efficacy of chemotherapy drugs such as cis-platin by resensitizing patients resistant to cisplatin treatment. The gene encoding NPRL2 is conserved between species and is expressed as two isoforms due to alternative splicing events.
Description
This is a NPRL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
NPRL2, FFEVF2, NPR2, NPR2L, TUSC4, NPR2-like
Gene ID
10641
Swiss Prot
Q8WTW4
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human NPRL2 (NP_006536.3) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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