KLKB1 Polyclonal Antibody

• Background :

  This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Description :

  This is a KLKB1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  KLKB1, KLK3, PKK, PKKD, PPK

• Gene ID :

  3818

• Swiss Prot :

  P03952

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human KLKB1 (NP_000883.2) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000 IHC 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  71 kDa

• Observed Molecular Weight :

  71 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG