TGFB2 Polyclonal Antibody

CAT: 0866-RD82941A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82941A-01Size:60 μL
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Background
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t (1;7) (q41; p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
Description
This is a TGFB2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
TGFB2, G-TSF, LDS4, TGF-beta2
Gene ID
7042
Swiss Prot
P61812
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human TGFB2 (NP_001129071.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:200-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
47 kDa/50 kDa
Observed Molecular Weight
55 kDa
Host or Source
Rabbit
Isotype
IgG

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