EPHB4 Polyclonal Antibody

• Background:

  Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

• Description:

  This is a EPHB4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  EPHB4, HFASD, HTK, MYK1, TYRO11

• Gene ID:

  2050

• Swiss Prot:

  P54760

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human EPHB4 (NP_004435.3) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:200-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  108 kDa

• Observed Molecular Weight:

  108 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG