LEPR Polyclonal Antibody

CAT: 0866-RD82816A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82816A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021) .
Description
This is a LEPR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CD295, LEP-R, LEPRD, OB-R, OBR, LEPR
Gene ID
3953
Swiss Prot
P48357
Reactivity
Human
Immunogen
A synthetic peptide of human LEPR
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
96 kDa/102 kDa/103 kDa/109 kDa/132 kDa
Observed Molecular Weight
113 kDa
Host or Source
Rabbit
Isotype
IgG

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