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DNMT3B Polyclonal Antibody

CAT: 0866-RD82794A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD82794A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
Description
This is a DNMT3B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
DNMT3B, ICF, ICF1, M.HsaIIIB
Gene ID
1789
Swiss Prot
Q9UBC3
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human DNMT3B
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:200-1:1000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
77-95 kDa
Observed Molecular Weight
110 kDa
Host or Source
Rabbit
Isotype
IgG

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