TLR2 Polyclonal Antibody

CAT: 0866-RD82675A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82675A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs) . Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.
Description
This is a TLR2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CD282, TIL4, TLR2
Gene ID
7097
Swiss Prot
O60603
Reactivity
Human
Immunogen
Recombinant fusion protein of human TLR2 (NP_003255.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
89 kDa
Observed Molecular Weight
100 kDa
Host or Source
Rabbit
Isotype
IgG

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