DMAP1 Polyclonal Antibody

• Background :

  This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

• Description :

  This is a DMAP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  DMAP1, DNMAP1, DNMTAP1, EAF2, MEAF2, SWC4

• Gene ID :

  55929

• Swiss Prot :

  Q9NPF5

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human DMAP1 (NP_061973.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:1000-1:4000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  52 kDa

• Observed Molecular Weight :

  60 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG