DMAP1 Polyclonal Antibody

• Background:

  This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

• Description:

  This is a DMAP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DMAP1, DNMAP1, DNMTAP1, EAF2, MEAF2, SWC4

• Gene ID:

  55929

• Swiss Prot:

  Q9NPF5

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human DMAP1 (NP_061973.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-1:4000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  52 kDa

• Observed Molecular Weight:

  60 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG