CHD3 Polyclonal Antibody

• Background:

  This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

• Description:

  This is a CHD3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CHD3, Mi-2a, Mi2-ALPHA, ZFH

• Gene ID:

  1107

• Swiss Prot:

  Q12873

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human CHD3 (NP_001005273.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:200-1:1000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  222 kDa/226 kDa/233 kDa

• Observed Molecular Weight:

  280 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG