CHD3 Polyclonal Antibody

• Background :

  This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

• Description :

  This is a CHD3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  CHD3, Mi-2a, Mi2-ALPHA, ZFH

• Gene ID :

  1107

• Swiss Prot :

  Q12873

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human CHD3 (NP_001005273.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:200-1:1000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  222 kDa/226 kDa/233 kDa

• Observed Molecular Weight :

  280 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG