CHIT1 Polyclonal Antibody

• Background:

  Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

• Description:

  This is a CHIT1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CHIT1, CHI3, CHIT, CHITD

• Gene ID:

  1118

• Swiss Prot:

  Q13231

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human CHIT1 (NP_003456.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG