CHIT1 Polyclonal Antibody

• Background :

  Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

• Description :

  This is a CHIT1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  CHIT1, CHI3, CHIT, CHITD

• Gene ID :

  1118

• Swiss Prot :

  Q13231

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein of human CHIT1 (NP_003456.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  IHC 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG