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BMPR1B Polyclonal Antibody

CAT: 0866-RD82465A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD82465A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.
Description
This is a BMPR1B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ALK-6, ALK6, AMDD, BDA1D, BDA2, CDw293, BMPR1B
Gene ID
658
Swiss Prot
O00238
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human BMPR1B (NP_001194.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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