ACVR2A Polyclonal Antibody

CAT: 0866-RD82451A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82451A-01Size:60 μL
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Background
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
Description
This is a ACVR2A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ACVR2A, ACTRII, ACVR2
Gene ID
92
Swiss Prot
P27037
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ACVR2A (NP_001607.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:100-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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