PSMB5 Polyclonal Antibody

CAT: 0866-RD82445A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82445A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit) . Multiple transcript variants encoding different isoforms have been found for this gene.
Description
This is a PSMB5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PSMB5, LMPX, MB1, X
Gene ID
5693
Swiss Prot
P28074
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PSMB5 (NP_002788.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
17 kDa/21 kDa/28 kDa
Observed Molecular Weight
21 kDa
Host or Source
Rabbit
Isotype
IgG

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