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UBE2D1 Polyclonal Antibody

CAT: 0866-RD82429A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD82429A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.
Description
This is a UBE2D1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
UBE2D1, E2 (17) KB1, SFT, UBC4/5, UBCH5, UBCH5A
Gene ID
7321
Swiss Prot
P51668
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human UBE2D1 (NP_003329.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
16 kDa
Observed Molecular Weight
14 kDa
Host or Source
Rabbit
Isotype
IgG

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