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THPO Polyclonal Antibody

CAT: 0866-RD82354A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD82354A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.
Description
This is a THPO Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
THPO, MGDF, MKCSF, ML, MPLLG, THCYT1, TPO
Gene ID
7066
Swiss Prot
P40225
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human THPO (NP_001171068.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33 kDa/37 kDa
Observed Molecular Weight
32 kDa
Host or Source
Rabbit
Isotype
IgG

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