BIN1 Polyclonal Antibody

CAT: 0866-RD82330A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82330A-01Size:60 μL
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Background
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Description
This is a BIN1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BIN1, AMPH2, AMPHL, SH3P9
Gene ID
274
Swiss Prot
O00499
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human BIN1 (NP_647601.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
45-64 kDa
Observed Molecular Weight
65 kDa
Host or Source
Rabbit
Isotype
IgG

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