HMBS Polyclonal Antibody

• Background:

  This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

• Description:

  This is a HMBS Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  HMBS, PBG-D, PBGD, PORC, UPS

• Gene ID:

  3145

• Swiss Prot:

  P08397

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human HMBS (NP_000181.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  33 kDa/34 kDa/37 kDa/39 kDa

• Observed Molecular Weight:

  45 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG