Products for Research Use Only
RegisterLogin

F12 Polyclonal Antibody

CAT: 0866-RD82282A-01Size: 60 μLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0866-RD82282A-01Size:60 μL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF) -like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.
Description
This is a F12 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
F12, HAE3, HAEX, HAF
Gene ID
2161
Swiss Prot
P00748
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human F12 (NP_000496.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
67 kDa
Observed Molecular Weight
71 kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RDR-F12-Mu-01Mouse Coagulation Factor XII (F12) ELISA Kit
RD-F12-Hu-96TestsHuman Coagulation Factor XII (F12) ELISA Kit
RDR-F12-Mu-48TestsMouse Coagulation Factor XII (F12) ELISA Kit
RD-F12-Mu-96TestsMouse Coagulation Factor XII (F12) ELISA Kit
RD-F12-Hu-48TestsHuman Coagulation Factor XII (F12) ELISA Kit
RDR-F12-Hu-96TestsHuman Coagulation Factor XII (F12) ELISA Kit
RD-F12-Mu-01Mouse Coagulation Factor XII (F12) ELISA Kit
RD-F12-Hu-01Human Coagulation Factor XII (F12) ELISA Kit
RDR-F12-Mu-96TestsMouse Coagulation Factor XII (F12) ELISA Kit
RDR-F12-Hu-48TestsHuman Coagulation Factor XII (F12) ELISA Kit

Alternative Products

CatalogName
APR12525GPolyclonal MeCP2 polyclonal antibody
APR00376GPolyclonal BMI1 polyclonal antibody
APR00459GPolyclonal CHD4 polyclonal antibody
APR00451GPolyclonal SPI1 polyclonal antibody
APR00373GPolyclonal EzH2 polyclonal antibody
APR14018GPolyclonal YY1 polyclonal antibody
PTX18700-100UCN3 Polyclonal Polyclonal Antibody
PTX18688-100TKT Polyclonal Polyclonal Antibody
PTX18684-100TGFA Polyclonal Polyclonal Antibody
PTX18678-100SYT1 Polyclonal Polyclonal Antibody

Popular Products