CD11B Polyclonal Antibody

• Background:

  This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3') . The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a CD11B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, ITGAM, CD11b/ITAM

• Gene ID:

  3684

• Swiss Prot:

  P11215

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human CD11B (NP_001139280.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG