GRAP Polyclonal Antibody

• Background :

  This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

• Description :

  This is a GRAP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  GRAP

• Gene ID :

  10750

• Swiss Prot :

  Q13588

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human GRAP (NP_006604.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:200-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  25 kDa

• Observed Molecular Weight :

  36 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG