GRAP Polyclonal Antibody

• Background:

  This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

• Description:

  This is a GRAP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  GRAP

• Gene ID:

  10750

• Swiss Prot:

  Q13588

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human GRAP (NP_006604.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:200-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  25 kDa

• Observed Molecular Weight:

  36 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG