UPF1 Polyclonal Antibody

• Background :

  This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD) . When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.

• Description :

  This is a UPF1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  UPF1, HUPF1, NORF1, RENT1, pNORF1, smg-2

• Gene ID :

  5976

• Swiss Prot :

  Q92900

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human UPF1 (NP_002902.2) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG