UPF1 Polyclonal Antibody

CAT: 0866-RD82041A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82041A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD) . When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.
Description
This is a UPF1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
UPF1, HUPF1, NORF1, RENT1, pNORF1, smg-2
Gene ID
5976
Swiss Prot
Q92900
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human UPF1 (NP_002902.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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