RNASEH2A Polyclonal Antibody

CAT: 0866-RD82018A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD82018A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2) . RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.
Description
This is a RNASEH2A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
RNASEH2A, AGS4, JUNB, RNASEHI, RNHIA, RNHL
Gene ID
10535
Swiss Prot
O75792
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human RNASEH2A (NP_006388.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33 kDa
Observed Molecular Weight
33 kDa
Host or Source
Rabbit
Isotype
IgG

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