SIM2 Polyclonal Antibody

• Background:

  This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.

• Description:

  This is a SIM2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  SIM2, HMC13F06, HMC29C01, SIM, bHLHe15

• Gene ID:

  6493

• Swiss Prot:

  Q14190

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human SIM2 (NP_033664.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  63 kDa/73 kDa

• Observed Molecular Weight:

  56 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG