CTTN Polyclonal Antibody

CAT: 0866-RD81988A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD81988A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Description
This is a CTTN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CTTN, EMS1, cortactin
Gene ID
2017
Swiss Prot
Q14247
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CTTN (NP_612632.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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