BCAM Polyclonal Antibody

• Background:

  This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu (a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a BCAM Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  BCAM, AU, CD239, LU, MSK19

• Gene ID:

  4059

• Swiss Prot:

  P50895

• Reactivity:

  Mouse

• Immunogen:

  Recombinant fusion protein of human BCAM (NP_005572.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  67 kDa

• Observed Molecular Weight:

  90 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG