Products for Research Use Only

OPRK1 Polyclonal Antibody

CAT: 0866-RD81686A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD81686A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Description
This is a OPRK1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
OPRK1, K-OR-1, KOR, KOR-1, OPRK
Gene ID
4986
Swiss Prot
P41145
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human OPRK1 (NP_000903.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33 kDa/42 kDa
Observed Molecular Weight
40 kDa
Host or Source
Rabbit
Isotype
IgG