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GNB3 Polyclonal Antibody

CAT: 0866-RD81627A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD81627A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Description
This is a GNB3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GNB3, CSNB1H
Gene ID
2784
Swiss Prot
P16520
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of human GNB3 (NP_002066.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
32 kDa/37 kDa
Observed Molecular Weight
37 kDa
Host or Source
Rabbit
Isotype
IgG

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