IDH3B Polyclonal Antibody

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+) . Five isocitrate dehydrogenases have been reported: three NAD (+) -dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+) -dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD (+) -dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD (+) -dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

This is a IDH3B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

IDH3B, RP46

3420

O43837

Human, Mouse, Rat

Recombinant fusion protein of human IDH3B (NP_008830.2) .

Unconjugated

Polyclonal Antibody

IF

Affinity purification

Antibody

1 mg/mL

IF 1:50-1:100

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Store at -20°C. Avoid freeze / thaw cycles.

Rabbit