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CAMLG Polyclonal Antibody

CAT: 0866-RD81583A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD81583A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Description
This is a CAMLG Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CAMLG, CAML, GET2
Gene ID
819
Swiss Prot
P49069
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CAMLG (NP_001736.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
32 kDa
Observed Molecular Weight
38 kDa
Host or Source
Rabbit
Isotype
IgG

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