BMI1 Polyclonal Antibody

• Background:

  This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1) . This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.

• Description:

  This is a BMI1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  BMI1, FLVI2/BMI1, PCGF4, RNF51, flvi-2/bmi-1, Bmi1

• Gene ID:

  648

• Swiss Prot:

  P35226

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human BMI1 (NP_005171.4) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  36 kDa

• Observed Molecular Weight:

  41 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG