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XRCC5 Polyclonal Antibody

CAT: 0866-RD81361A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD81361A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Description
This is a XRCC5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
XRCC5, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV
Gene ID
7520
Swiss Prot
P13010
Reactivity
Human
Immunogen
Recombinant fusion protein of human XRCC5 (NP_066964.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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