PIWIL4 Polyclonal Antibody

• Background:

  PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association.

• Description:

  This is a PIWIL4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PIWIL4, HIWI2, MIWI2

• Gene ID:

  143689

• Swiss Prot:

  Q7Z3Z4

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human PIWIL4 (NP_689644.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  52 kDa/56 kDa/96 kDa

• Observed Molecular Weight:

  105 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG