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PIWIL4 Polyclonal Antibody

CAT: 0866-RD81272A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD81272A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association.
Description
This is a PIWIL4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PIWIL4, HIWI2, MIWI2
Gene ID
143689
Swiss Prot
Q7Z3Z4
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PIWIL4 (NP_689644.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
52 kDa/56 kDa/96 kDa
Observed Molecular Weight
105 kDa
Host or Source
Rabbit
Isotype
IgG

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