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LEP Polyclonal Antibody

CAT: 0866-RD81177A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD81177A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
Description
This is a LEP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
LEP, LEPD, OB, OBS, leptin
Gene ID
3952
Swiss Prot
P41159
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human LEP (NP_000221.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
18 kDa
Observed Molecular Weight
17 kDa
Host or Source
Rabbit
Isotype
IgG

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