COMT Polyclonal Antibody

CAT: 0866-RD81154A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD81154A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT) . The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
Description
This is a COMT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
COMT, HEL-S-98n
Gene ID
1312
Swiss Prot
P21964
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human COMT (NP_009294.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
24 kDa/30 kDa
Observed Molecular Weight
25 kDa/30 kDa
Host or Source
Rabbit
Isotype
IgG

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