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CHRFAM7A Polyclonal Antibody

CAT: 0866-RD81036A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD81036A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A) . Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
Description
This is a CHRFAM7A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CHRFAM7A, CHRNA7, CHRNA7-DR1, D-10
Gene ID
89832
Swiss Prot
Q494W8
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CHRFAM7A (NP_647536.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46 kDa
Observed Molecular Weight
50 kDa
Host or Source
Rabbit
Isotype
IgG

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