HDAC3 Polyclonal Antibody

• Background:

  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

• Description:

  This is a HDAC3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  HD3, RPD3, RPD3-2, HDAC3

• Gene ID:

  8841

• Swiss Prot:

  O15379

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human HDAC3 (NP_003874.2) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  48 kDa/49 kDa

• Observed Molecular Weight:

  48 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG