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HDAC3 Polyclonal Antibody

CAT: 0866-RD80997A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD80997A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Description
This is a HDAC3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
HD3, RPD3, RPD3-2, HDAC3
Gene ID
8841
Swiss Prot
O15379
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human HDAC3 (NP_003874.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48 kDa/49 kDa
Observed Molecular Weight
48 kDa
Host or Source
Rabbit
Isotype
IgG

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