SHMT1 Polyclonal Antibody

• Background:

  This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.

• Description:

  This is a SHMT1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  SHMT1, CSHMT, SHMT

• Gene ID:

  6470

• Swiss Prot:

  P34896

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human SHMT1 (NP_683718.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  37 kDa/44 kDa/49 kDa/53 kDa

• Observed Molecular Weight:

  53 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG