OGDH Polyclonal Antibody

• Background :

  This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO (2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

• Description :

  This is a OGDH Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  OGDH, AKGDH, E1k, OGDC

• Gene ID :

  4967

• Swiss Prot :

  Q02218

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human OGDH (NP_001003941.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  IHC 1:50-1:200 IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG