CD3E Antigen Polyclonal Antibody

• Background:

  The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

• Description:

  This is a CD3E Antigen Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CD3E, IMD18, T3E, TCRE, CD3e molecule

• Gene ID:

  916

• Swiss Prot:

  P07766

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human CD3E Antigen (NP_000724.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  23 kDa

• Observed Molecular Weight:

  23-25 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG