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COASY Polyclonal Antibody

CAT: 0866-RD80820A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD80820A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5) . The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA) . Alternative splicing results in multiple isoforms.
Description
This is a COASY Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
COASY, DPCK, NBIA6, NBP, PPAT, UKR1, pOV-2
Gene ID
80347
Swiss Prot
Q13057
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human COASY (NP_079509.5) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
62 kDa/65 kDa
Observed Molecular Weight
62 kDa
Host or Source
Rabbit
Isotype
IgG

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